Selected publications

M. Botou, V. Yalelis, P. Lazou, I. Zantza, K. Papakostas, V. Charalambous, E. Mikros, E. Flemetakis, and S. Frillingos, Specificity profile of NAT/NCS2 purine transporters in Sinorhizobium (Ensifer) meliloti, Mol. Microbiol. (2020) in press.

M. Botou, P. Lazou, K. Papakostas, G. Lambrinidis, T. Evangelidis, E. Mikros, and S. Frillingos, Insight on specificity of uracil permeases of the NAT/NCS2 family from analysis of the transporter encoded in the pyrimidine utilization operon of Escherichia coli. Mol. Microbiol. 108, 204-219 (2018)

E. Karena, E. Tatsaki, G. Lambrinidis, E. Mikros, and S. Frillingos, Analysis of conserved NCS2 motifs in the Escherichia coli xanthine permease XanQ, Mol. Microbiol. 98, 502-517 (2015)

K. Papakostas, M. Botou, and S. Frillingos, Functional identification of the hypoxanthine/guanine transporters YjcD and YgfQ and the adenine transporters PurP and YicO of Escherichia coli K-12, J. Biol. Chem. 288, 36827-36840 (2013).

E. Karena and S. Frillingos, The role of transmembrane segment TM3 in the xanthine permease XanQ of Escherichia coli, J. Biol. Chem. 286, 39595-39605 (2011).

E. Georgopoulou, G. Mermelekas, E. Karena, and S. Frillingos, «Purine substrate recognition by the nucleobase-ascorbate transporter motif in the YgfO xanthine permease: Asn-325 binds and Ala-323 senses substrate», J. Biol. Chem. 285, 19422-19433 (2010).

H. R. Kaback, R. Dunten, S. Frillingos, P. Venkatesan, I. Kwaw, W. Zhang, and N. Ermolova, «Site-directed alkylation and the alternating access model for LacY», Proc. Natl. Acad. Sci. USA 104,491-494 (2007).

P. Karatza, and S. Frillingos, «Cloning and functional characterization of two bacterial members of the NAT/NCS2 family in Escherichia coli», Mol. Membr. Biol. 22, 251-261 (2005).

S. Frillingos, M. Sahin-Tόth, J. Wu, and H. R. Kaback, «Cys-scanning mutagenesis: a novel approach to structure-function relationships in membrane proteins», FASEB J. 12, 1281-1299 (1998).